Axillary fibromatosis with radiological-pathological correlation: a case report and literature review

Abstract Background The term fibromatosis refers to a spectrum of soft tissue tumors resulting from the unbridled proliferation fibroblasts, with high infiltrative power. It is rare neoplasm, an incidence about 3 cases per million. Most common sites include abdominal wall and cavity, chest wall, scapular area, limbs, rarely affecting axilla. Imaging plays major role in surgical planning clinical follow-up. Differential diagnosis other may be arduous, but correct evaluation fundamental. Case presentation A 33-year-old case reported for palpable hardened immobile left axillary nodule. ultrasound reveals solid, elongated, heterogeneous, poorly delimited, lesion observed hollow, no detectable flow color Doppler mode. At magnetic resonance imaging, same elongated expansive was better defined, revealing its irregular contours, alternating areas hypo- hyperintense on T2, heterogeneous enhancement, signs signal decay in- out-of-phase sequences. Due growth local invasion potential, excision performed. microscopic analysis showed long uniform spindle cell fascicles, clear cytoplasm wavy nuclei, arranged different directions, included collagen stroma. Immunohistochemistry positive nuclear beta-catenin, confirming fibromatosis. Conclusion methods reflect nature lesion. This study demonstrates importance using multidisciplinary approach addition imaging tests histopathological therapeutic planning. power always must reminded of, since it affects young patients delay can lead mutilating surgeries.